Alpha smooth muscle actin Antibody

• Background:

  The protein encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Defects in this gene cause aortic aneurysm familial thoracic type 6. Multiple alternatively spliced variants, encoding the same protein, have been identified.

• NCBI Gene ID:

  59

• Swiss Prot:

  P62736

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-377 of human alpha smooth muscle actin (NP_001135417.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Neuroscience, Signal Transduction, Stem Cell

• Purification:

  Affinity purification

• Positive Control:

  SW480

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 42kDa

• Fragment:

  IgG

• Symbol:

  ACTA2

• Positive Control 2:

  MCF7

• Positive Control 3:

  HeLa

• Positive Control 4:

  HepG2

• Positive Control 5:

  Mouse heart

• Positive Control 6:

  Mouse testis

• NCBI Official Name:

  Actin, alpha 2, smooth muscle, aorta

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  ACTA2, ACTSA, actin, alpha 2, smooth muscle, aorta, alpha-cardiac actin, ACTVS, GIG46

• Tested Applications:

  WB, IF

• Physical Properties:

  Liquid