PDIA6 Antibody

• Background:

  This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, two catalytically active thioredoxin (TRX) domains, a TRX-like domain, and a C-terminal ER-retention sequence. This protein inhibits the aggregation of misfolded proteins and exhibits both isomerase and chaperone activity. Alternative splicing results in multiple transcript variants encoding different isoforms.

• NCBI Gene ID:

  10130

• Swiss Prot:

  Q15084

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 20-300 of human PDIA6 (NP_005733.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  HL-60

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 48kDa

• Fragment:

  IgG

• Symbol:

  PDIA6

• Positive Control 2:

  SW480

• Positive Control 3:

  HepG2

• Positive Control 4:

  THP-1

• Positive Control 5:

  Mouse liver

• Positive Control 6:

  Mouse lung

• NCBI Official Name:

  Protein disulfide isomerase family A, member 6

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  PDIA6, ERP5, P5, TXNDC7

• Tested Applications:

  WB, IHC, IF

• Physical Properties:

  Liquid