SARS-CoV-2 (COVID-19) NSP16 Antibody

• Background:

  The coronaviral proteases, papain-like protease (PLpro) and 3C-like protease (3CLpro), are attractive antiviral drug targets because they are essential for coronaviral replication. PLpro has the additional function of stripping ubiquitin and ISG15 from host-cell proteins to aid coronaviruses in their evasion of the host innate immune responses. Targeting PLpro with antiviral drugs may have an advantage in not only inhibiting viral replication but also inhibiting the dysregulation of signaling cascades in infected cells that may lead to cell death in surrounding, uninfected cells.

• NCBI Gene ID:

  43740578

• Swiss Prot:

  P0DTC1

• Host:

  Sheep

• Reactivity:

  Virus

• Immunogen:

  GST-SARS-CoV2 NSP16

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Infectious Disease, COVID-19

• Purification:

  Antibodies are affinity purified against the antigen and eluted with low pH.

• Concentration:

  Batch dependent

• Buffer:

  Antibody supplied in PBS.

• Modification:

  None

• Shipping Conditions:

  Dry Ice

• Storage Conditions:

  Aliquot and store at -20˚ C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Observed Molecular Weight:

  60 kDa

• Symbol:

  ORF1ab

• NCBI Official Name:

  ORF1a polyprotein; ORF1ab polyprotein

• NCBI Organism:

  Severe acute respiratory syndrome coronavirus 2

• Other Product Names:

  SARS-CoV-2-NSP16

• Tested Applications:

  WB

• Physical Properties:

  Liquid