CSTA Antibody

• Background:

  The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins, and kininogens. This gene encodes a stefin that functions as a cysteine protease inhibitor, forming tight complexes with papain and the cathepsins B, H, and L. The protein is one of the precursor proteins of cornified cell envelope in keratinocytes and plays a role in epidermal development and maintenance. Stefins have been proposed as prognostic and diagnostic tools for cancer.

• NCBI Gene ID:

  1475

• Swiss Prot:

  P01040

• Host:

  Rabbit

• Reactivity:

  Human, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-98 of human CSTA (NP_005204.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Apoptosis, Cancer, Cell Cycle, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  THP-1

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 13kDa

• Fragment:

  IgG

• Symbol:

  CSTA

• NCBI Official Name:

  Cystatin-A

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Cystatin-A, Cystatin-AS, Stefin-A, Cystatin-A, N-terminally processed, CSTA, STF1, STFA

• Tested Applications:

  WB, IHC, IF

• Physical Properties:

  Liquid