NPC2 Antibody

• Background:

  This gene encodes a protein containing a lipid recognition domain. The encoded protein may function in regulating the transport of cholesterol through the late endosomal/lysosomal system. Mutations in this gene have been associated with Niemann-Pick disease, type C2 and frontal lobe atrophy.

• NCBI Gene ID:

  10577

• Swiss Prot:

  P61916

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 20-151 of human NPC2 (NP_006423.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Neuroscience, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  Mouse lung

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 19kDa

• Fragment:

  IgG

• Symbol:

  NPC2

• NCBI Official Name:

  Niemann-Pick disease, type C2

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  NPC2, tissue-specific secretory protein, NP-C2, Niemann-Pick disease, type C2, MGC1333, HE1, epididymal secretory protein E1, epididymal secretory protein, epididymal protein 1, EDDM1

• Tested Applications:

  WB, IHC

• Physical Properties:

  Liquid