MRPL1 Antibody

• Background:

  Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L1 ribosomal protein family.

• NCBI Gene ID:

  65008

• Swiss Prot:

  Q9BYD6

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 51-325 of human MRPL1 (NP_064621.3) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  Affinity purification

• Positive Control:

  A-431

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 37kDa

• Fragment:

  IgG

• Symbol:

  MRPL1

• Positive Control 2:

  MCF7

• Positive Control 3:

  HeLa

• Positive Control 4:

  Jurkat

• NCBI Official Name:

  39S ribosomal protein L1, mitochondrial

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  39S ribosomal protein L1, mitochondrial, L1mt, MRP-L1, MRPL1

• Tested Applications:

  WB, IHC

• Physical Properties:

  Liquid