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GALNT4 Antibody

CAT: 0223-19-318Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-19-318Size:100 µL
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Background
This gene encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins. They are characterized by an N-terminal transmembrane domain, a stem region, a lumenal catalytic domain containing a GT1 motif and Gal/GalNAc transferase motif, and a C-terminal ricin/lectin-like domain. GalNAc-Ts have different, but overlapping, substrate specificities and patterns of expression. In vitro, the encoded protein can complement other GalNAc-Ts in the complete O-glycosylation of the mucin-1 tandem repeat and can O-glycosylate the P-selectin glycoprotein ligand-1 molecule. The coding region of this gene is contained within a single exon. Fusion transcripts, which combine part of this gene with the 5' exons of the neighboring POC1B (POC1 centriolar protein homolog B) gene, also exist.
NCBI Gene ID
8693
Swiss Prot
Q8N4A0
Host
Rabbit
Reactivity
Human
Immunogen
A synthetic Peptide of human GALNT4
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Affinity purification
Positive Control
HeLa
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 57kDa
Fragment
IgG
Symbol
GALNT4
NCBI Official Name
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4)
NCBI Organism
Homo sapiens
Other Product Names
GALNT4, GALNAC-T4, GalNAcT4, GALNACT4
Tested Applications
WB, Flow
Physical Properties
Liquid