TNFRSF4 Antibody

• Background:

  The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation.

• NCBI Gene ID:

  7293

• Swiss Prot:

  P43489

• Host:

  Rabbit

• Reactivity:

  Rat

• Immunogen:

  A synthetic peptide corresponding to a sequence within amino acids 100-200 of human TNFRSF4 (NP_003318.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Chemokines & Cytokines, Immunology, Innate Immunity, Stem Cell

• Purification:

  Affinity purification

• Positive Control:

  Rat liver

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 48kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:2000

• Symbol:

  TNFRSF4

• NCBI Official Name:

  TNF receptor superfamily member 4

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  ACT35, CD134, IMD16, OX4TXGP1L, tumor necrosis factor receptor superfamily member 4, ACT35 antigen, ATC35 antigen, CD134 antigen, OX40 antigen, OX40 cell surface antigen, OX40 homologue, OX40L receptor, TAX transcriptionally-activated glycoprotein 1 receptor, lymphoid activation antigene ACT35, tax-transcriptionally activated glycoprotein 1 receptor

• Tested Applications:

  WB

• Physical Properties:

  Liquid