Asymmetric DiMethyl-Histone H3-R8 pAb

• Background:

  Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4) . The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.

• NCBI Gene ID:

  8290

• Swiss Prot:

  Q16695

• Host:

  Rabbit

• Reactivity:

  Mouse, Rat

• Immunogen:

  A synthetic methylated peptide corresponding to residues surrounding R8 of human histone H3

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  HeLa

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  Methylated

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 17kDa

• Fragment:

  IgG

• Symbol:

  H3R8me2a

• Positive Control 2:

  H3 protein

• NCBI Official Name:

  Histone cluster 3, H3

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  H3F3A, H3t, H3.4, H3/g, H3FT

• Tested Applications:

  WB, IHC, IF

• Physical Properties:

  Liquid