NOTCH3 Antibody

CAT: 0223-18-949Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-18-949Size:100 µL
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) .
NCBI Gene ID
4854
Swiss Prot
Q9UM47
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
A synthetic peptide of human NOTCH3
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Neuroscience, Signal Transduction, Stem Cell, Transcription
Purification
Affinity purification
Positive Control
293T
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 90kDa/280kDa
Fragment
IgG
Symbol
NOTCH3
NCBI Official Name
Notch 3
NCBI Organism
Homo sapiens
Other Product Names
NOTCH3, Notch homolog 3 (Drosophila), HGNC:7883, CADASIL, CASIL, Notch (Drosophila) homolog 3, Notch homolog 3, IMF2
Tested Applications
WB, IF
Physical Properties
Liquid

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