IGF2 Antibody

• Background:

  This gene encodes a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele, and epigenetic changes at this locus are associated with Wilms tumour, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, and Silver-Russell syndrome. A read-through INS-IGF2 gene exists, whose 5' region overlaps the INS gene and the 3' region overlaps this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

• NCBI Gene ID:

  3481

• Swiss Prot:

  P01344

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 25-180 of human IGF2 (NP_000603.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle, Growth Factors, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  HepG2

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 28kDa

• Fragment:

  IgG

• Symbol:

  IGF2

• Positive Control 2:

  SW480

• Positive Control 3:

  Mouse brain

• NCBI Official Name:

  Insulin-like growth factor 2 (somatomedin A)

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  IGF2, somatomedin-A, PP9974, OTTHUMP00000220677, insulin-like growth factor type 2, insulin-like growth factor II, insulin-like growth factor 2 (somatomedin A), IGF-II, FLJ44734, FLJ22066, C11orf43

• Tested Applications:

  WB, IF

• Physical Properties:

  Liquid