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GSTA3 Antibody

CAT: 0223-16-957Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-16-957Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class genes that are located in a cluster mapped to chromosome 6. Genes of the alpha class are highly related and encode enzymes with glutathione peroxidase activity. However, during evolution, this alpha class gene diverged accumulating mutations in the active site that resulted in differences in substrate specificity and catalytic activity. The enzyme encoded by this gene catalyzes the double bond isomerization of precursors for progesterone and testosterone during the biosynthesis of steroid hormones. An additional transcript variant has been identified, but its full length sequence has not been determined. [provided by RefSeq, Jul 2008]
NCBI Gene ID
2940
Swiss Prot
Q16772
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-222 of human GSTA3 (NP_000838.3) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Growth Factors, Signal Transduction
Purification
Affinity purification
Positive Control
PC-3
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 25kDa
Fragment
IgG
Symbol
GSTA3
Positive Control 2
293T
Positive Control 3
Mouse lung
Positive Control 4
Mouse liver
Positive Control 5
Mouse kidney
Positive Control 6
Rat kidney
NCBI Official Name
Glutathione S-transferase alpha 3
NCBI Organism
Homo sapiens
Other Product Names
GSTA3, GST class-alpha member 3, GSTA3-3, Glutathione S-transferase A3, GTA3, Glutathione S-transferase A3-3
Tested Applications
WB, IF
Physical Properties
Liquid

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