CAST Antibody

• Background :

  The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described.

• NCBI Gene ID :

  831

• Swiss Prot :

  P20810

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-350 of human CAST (NP_001177371.1) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cell Cycle, Neuroscience

• Purification :

  Affinity purification

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Fragment :

  IgG

• Symbol :

  CAST

• NCBI Official Name :

  Calpastatin

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  Calpastatin, Calpain inhibitor, BS-17, Calpastatin

• Tested Applications :

  WB, IHC

• Physical Properties :

  Liquid