CYP1B1 Antibody

• Background:

  This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The enzyme encoded by this gene localizes to the endoplasmic reticulum and metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17beta-estradiol. Mutations in this gene have been associated with primary congenital glaucoma; therefore it is thought that the enzyme also metabolizes a signaling molecule involved in eye development, possibly a steroid.

• NCBI Gene ID:

  1545

• Swiss Prot:

  Q16678

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 244-543 of human CYP1B1 (NP_000095.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Neuroscience, Signal Transduction

• Purification:

  Affinity purification

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Fragment:

  IgG

• Symbol:

  CYP1B1

• NCBI Official Name:

  Cytochrome P450, family 1, subfamily B, polypeptide 1

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  CYP1B1, CP1B, GLC3A, CYPIB1, P4501B1

• Tested Applications:

  WB, IF

• Physical Properties:

  Liquid