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SEPT5 Antibody

CAT: 0223-14-722Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-14-722Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB; platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced.
NCBI Gene ID
5413
Swiss Prot
Q99719
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-369 of human SEPT5 (NP_002679.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Chemokines & Cytokines, Immunology, Neuroscience, Signal Transduction
Purification
Affinity purification
Positive Control
Jurkat
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 43kDa
Fragment
IgG
Symbol
SEPT5.
Positive Control 2
NIH/3T3
Positive Control 3
Mouse brain
Positive Control 4
Mouse heart
Positive Control 5
Mouse kidney
Positive Control 6
Rat brain
NCBI Official Name
Septin 5
NCBI Organism
Homo sapiens
Other Product Names
SEPT5, CDCREL-1, CDCREL1, H5, HCDCREL-1, Peanut-like 1 (Drosophila), Peanut-like 1, Peanut-like protein 1, Septin 5, Septin-5, CDCREL, PNUTL1
Tested Applications
WB, IHC
Physical Properties
Liquid

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