IL17A Antibody

• Background :

  The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO) . High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.

• NCBI Gene ID :

  3605

• Swiss Prot :

  Q16552

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Recombinant fusion protein containing a sequence corresponding to amino acids 24-155 of human IL17A (NP_002181.1) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Apoptosis, Cancer, Cell Cycle, Chemokines & Cytokines, Immunology, Innate Immunity

• Purification :

  Affinity purification

• Positive Control :

  U-937

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  Observed: 37kDa

• Fragment :

  IgG

• Symbol :

  IL17A

• Positive Control 2 :

  Raji

• Positive Control 3 :

  Jurkat

• Positive Control 4 :

  SW620

• Positive Control 5 :

  Mouse thymus

• NCBI Official Name :

  Interleukin 17A

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  Interleukin-17A; CTLA-8; Cytotoxic T Lymphocyte-associated Antigen 8

• Tested Applications :

  WB, IHC

• Physical Properties :

  Liquid