IL17A Antibody

• Background:

  The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO) . High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.

• NCBI Gene ID:

  3605

• Swiss Prot:

  Q16552

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 24-155 of human IL17A (NP_002181.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Apoptosis, Cancer, Cell Cycle, Chemokines & Cytokines, Immunology, Innate Immunity

• Purification:

  Affinity purification

• Positive Control:

  U-937

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 37kDa

• Fragment:

  IgG

• Symbol:

  IL17A

• Positive Control 2:

  Raji

• Positive Control 3:

  Jurkat

• Positive Control 4:

  SW620

• Positive Control 5:

  Mouse thymus

• NCBI Official Name:

  Interleukin 17A

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Interleukin-17A; CTLA-8; Cytotoxic T Lymphocyte-associated Antigen 8

• Tested Applications:

  WB, IHC

• Physical Properties:

  Liquid