CNTFR Antibody

• Background :

  This gene encodes a member of the type 1 cytokine receptor family. The encoded protein is the ligand-specific component of a tripartite receptor for ciliary neurotrophic factor, which plays a critical role in neuronal cell survival, differentiation and gene expression. Binding of ciliary neurotrophic factor to the encoded protein recruits the transmembrane components of the receptor, gp130 and leukemia inhibitory factor receptor, facilitating signal transduction. Single nucleotide polymorphisms in this gene may be associated with variations in muscle strength, as well as early onset of eating disorders. Alternatively spliced transcript variants have been observed for this gene.

• NCBI Gene ID :

  1271

• Swiss Prot :

  P26992

• Host :

  Rabbit

• Reactivity :

  Human, Rat

• Immunogen :

  Recombinant fusion protein containing a sequence corresponding to amino acids 90-342 of human CNTFR (NP_671693.1) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Neuroscience, Signal Transduction

• Purification :

  Affinity purification

• Positive Control :

  SH-SY5Y

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  Observed: 41kDa

• Fragment :

  IgG

• Symbol :

  CNTFR

• NCBI Official Name :

  Ciliary neurotrophic factor receptor

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  CNTFR, ciliary neurotrophic factor receptor, MGC1774, CNTFR alpha, ciliary neurotrophic factor receptor alpha precursor

• Tested Applications :

  WB, IHC

• Physical Properties :

  Liquid