CD3D Antibody

• Background :

  The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK) . Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined.

• NCBI Gene ID :

  915

• Swiss Prot :

  P04234

• Host :

  Rabbit

• Reactivity :

  Human, Rat

• Immunogen :

  Recombinant fusion protein containing a sequence corresponding to amino acids 22-105 of human CD3D (NP_000723.1) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cancer, Immunology, Stem Cell

• Purification :

  Affinity purification

• Positive Control :

  Jurkat

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  Observed: 19kDa

• Fragment :

  IgG

• Symbol :

  CD3D

• NCBI Official Name :

  CD3d molecule, delta (CD3-TCR complex)

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  CD3D, CD3d molecule, delta (CD3-TCR complex), CD3-DELTA, IMD19, T3D, CD3 antigen, delta subunit, CD3 delta, CD3d antigen, delta polypeptide (TiT3 complex), OKT3, delta chain, T-cell receptor T3 delta chain, T-cell surface glycoprotein CD3 delta chain

• Tested Applications :

  WB, IHC, IF

• Physical Properties :

  Liquid