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EPHA8 Antibody

CAT: 0223-13-505Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-13-505Size:100 µL
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Background
This gene encodes a member of the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. The protein encoded by this gene functions as a receptor for ephrin A2, A3 and A5 and plays a role in short-range contact-mediated axonal guidance during development of the mammalian nervous system.
NCBI Gene ID
2046
Swiss Prot
P29322
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 28-300 of human EPHA8 (NP_001006944.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience, Signal Transduction
Purification
Affinity purification
Positive Control
U-87MG
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 111kDa
Fragment
IgG
Applications Notes
WB: 1:1000 - 1:2000
Symbol
EPHA8
Positive Control 2
B cells
Positive Control 3
Mouse liver
Positive Control 4
Mouse heart
Positive Control 5
Mouse pancreas
Positive Control 6
Mouse brain
NCBI Official Name
EPH receptor A8
NCBI Organism
Homo sapiens
Other Product Names
EEK, EK3, HEK3, ephrin type-A receptor 8, EPH- and ELK-related kinase, EPH- and ELK-related tyrosine kinase, EPH-like kinase 3, hydroxyaryl-protein kinase, protein-tyrosine kinase, tyrosine-protein kinase receptor EEK, tyrosylprotein kinase
Tested Applications
WB
Physical Properties
Liquid

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