BIRC3 Antibody

CAT: 0223-13-293Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-13-293Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the IAP family of proteins that inhibit apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. It contains 3 baculovirus IAP repeats and a ring finger domain. Transcript variants encoding the same isoform have been identified.
NCBI Gene ID
330
Swiss Prot
Q13489
Host
Rabbit
Reactivity
Human
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human BIRC3 (NP_001156.1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis, Cancer, Cell Cycle, Immunology
Purification
Affinity purification
Positive Control
U-937
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 68kDa
Fragment
IgG
Symbol
BIRC3
NCBI Official Name
Baculoviral IAP repeat containing 3
NCBI Organism
Homo sapiens
Other Product Names
BIRC3, TNFR2-TRAF signaling complex protein, RNF49, MIHC, MALT2, HIAP1, HAIP1, c-IAP2, CIAP2, baculoviral IAP repeat-containing protein 3, baculoviral IAP repeat-containing 3, apoptosis inhibitor 2, API2, AIP1, IAP1
Tested Applications
WB, IF
Physical Properties
Liquid

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