BIRC3 Antibody

• Background :

  This gene encodes a member of the IAP family of proteins that inhibit apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. It contains 3 baculovirus IAP repeats and a ring finger domain. Transcript variants encoding the same isoform have been identified.

• NCBI Gene ID :

  330

• Swiss Prot :

  Q13489

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human BIRC3 (NP_001156.1) .

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Apoptosis, Cancer, Cell Cycle, Immunology

• Purification :

  Affinity purification

• Positive Control :

  U-937

• Concentration :

  Batch dependent

• Buffer :

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  Observed: 68kDa

• Fragment :

  IgG

• Symbol :

  BIRC3

• NCBI Official Name :

  Baculoviral IAP repeat containing 3

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  BIRC3, TNFR2-TRAF signaling complex protein, RNF49, MIHC, MALT2, HIAP1, HAIP1, c-IAP2, CIAP2, baculoviral IAP repeat-containing protein 3, baculoviral IAP repeat-containing 3, apoptosis inhibitor 2, API2, AIP1, IAP1

• Tested Applications :

  WB, IF

• Physical Properties :

  Liquid