SARS-CoV-2 (COVID-19) NSP2 Antibody

• Background:

  Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus (1) . The disease is the cause of the 2019–20 coronavirus outbreak (2) . The structure of 2019-nCoV consists of the following: a spike protein (S), hemagglutinin-esterease dimer (HE), a membrane glycoprotein (M), an envelope protein (E) a nucleoclapid protein (N) and RNA. NSP2 may play a role in the modulation of host cell survival signaling pathway by interacting with host PHB and PHB2. Indeed, these two proteins play a role in maintaining the functional integrity of the mitochondria and protecting cells from various stresses (3) .

• NCBI Gene ID:

  43740578

• Swiss Prot:

  P0DTC1

• Accession Number:

  YP_009742609.1

• Host:

  Rabbit

• Reactivity:

  Virus

• Immunogen:

  9171

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Infectious Disease, COVID-19

• Purification:

  SARS-CoV-2 (COVID-19) NSP2 Antibody is affinity chromatography purified via peptide column.

• Concentration:

  1 mg/mL

• Homology:

  Predicted reactivity based on immunogen sequence: SARS-CoV NSP2 protein: (79%)

• Buffer:

  SARS-CoV-2 (COVID-19) NSP2 Antibody is supplied in PBS containing 0.02% sodium azide.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  SARS-CoV-2 (COVID-19) NSP2 antibody can be stored at 4 ˚ C for three months and -20 ˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Fragment:

  IgG

• Symbol:

  Non-structural protein 2

• NCBI Official Name:

  ORF1a polyprotein; ORF1ab polyprotein

• NCBI Organism:

  Severe acute respiratory syndrome coronavirus 2

• Background Reference 01:

  Gorbalenya. bioRxiv: 2020.

• Background Reference 02:

  Hui et al. Int J Infect Dis. 2020;91:264-266.

• Background Reference 03:

  Cornillez-Ty et al. J.Virol. 2019; 83:10314-10318

• Other Product Names:

  NSP2, p65 homolog

• Tested Applications:

  ELISA, WB

• Protein ID:

  1826688919

• Physical Properties:

  Liquid