Gp120 Antibody

• Background:

  Human immunodeficiency virus type 1 (HIV-1) entry into target cells is directed by the envelope (Env) glycoproteins, which are present on the surface of HIV-1 virion or infected cells in the form of trimers consisting of gp120/gp41 complexes. The surface subunit, gp120, initiates the entry process by interacting sequentially with the CD4 receptor and a co-receptor CCR5 or CXCR4, thereby inducing a conformational change that allows the transmembrane (TM) gp41 subunit to mediate fusion between viral and target cell membranes. Cleavage of Env into its gp120 and gp41 components is necessary for activation of its fusogenic activity.

• NCBI Gene ID:

  155971

• Swiss Prot:

  P04578

• Accession Number:

  AAB05604

• Host:

  Rabbit

• Reactivity:

  HIV-1

• Immunogen:

  Gp120 antibody was raised against a peptide corresponding to 15 amino acids near the center of HIV-1 gp120.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Infectious Disease

• Purification:

  Gp120 Antibody is affinity chromatography purified via peptide column.

• Concentration:

  1 mg/mL

• Buffer:

  Gp120 Antibody is supplied in PBS containing 0.02% sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Gp120 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Fragment:

  IgG

• Applications Notes:

  Gp120 antibody can be used for Western blot at 1 - 2 μ g/mL.

• Symbol:

  Gp120

• NCBI Official Name:

  Env

• NCBI Organism:

  HIV-1

• Other Product Names:

  Gp120 Antibody: Envelope glycoprotein gp160

• Tested Applications:

  ELISA, WB

• Protein ID:

  1465781

• Physical Properties:

  Liquid