Products for Research Use Only
RegisterLogin

ARID1A Antibody

CAT: 0223-8173-01Size: 0.02 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-8173-01Size:0.02 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
The ARID1A protein is a member of the SWI/SNF family, whose members are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. ARID1A is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin (1) . It possesses a DNA-binding domain that can specifically bind an AT-rich DNA sequence known to be recognized by a SNF/SWI complex at the beta-globin locus. The C-terminus of the protein can stimulate glucocorticoid receptor-dependent transcriptional activation. It is thought that ARID1A confers specificity to the SNF/SWI complex and may recruit the complex to its targets through either protein-DNA or protein-protein interactions (2) .
NCBI Gene ID
8289
Swiss Prot
O14497
Accession Number
NP_006006
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Homeostasis, Signal Transduction
Purification
ARID1A antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1220 - SK-N-SH Cell Lysate
Concentration
1 mg/mL
Buffer
ARID1A antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
ARID1A antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.
Fragment
IgG
Specificity
ARID1A antibody is human, mouse and rat reactive. Multiple isoforms of ARID1A protein are known to exist.
Symbol
ARID1A
NCBI Official Name
AT rich interactive domain 1A (SWI-like)
NCBI Organism
Homo sapiens
Background Reference 01
Martens JA and Winston F. Recent advances in understanding chromatin remodeling by Swi/Snf complexes. Curr. Opin. Genet. Dev. 2003; 13:136-42.
Background Reference 02
Nie Z, Xue Y, Yang D, et al. A specificity and targeting subunit of a human SWI/SNF family-related chromatin-remodeling complex. Mol. Cell. Biol. 2000; 20:8879-88.
Other Product Names
AT rich interactive domain 1A (SWI-like), RP1-50O24.1, B120, BAF250, BAF250a, BM029, C1orf4, ELD, hELD, MRD14, OSA1, hOSA1, P270, SMARCF1
Tested Applications
ELISA, WB, IHC-P, IF
Protein ID
21264565
Physical Properties
Liquid

Related Products

CatalogName
8173PARID1A Peptide
27-729ARID3A Antibody
26-570ARID5A Antibody
23-092ARID3A Antibody
27-784ARID4A Antibody
26-569ARID5A Antibody
59-331ARID5A Antibody
25-441ARID3A Antibody
59-209ARID5B Antibody
28-946ARID3B Antibody

Alternative Products

CatalogName
10R-1290ARID1A antibody

Popular Products