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PROM1 Antibody

CAT: 0223-7783-01Size: 0.02 mgDry Ice: NoHazardous: No
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CAT#:0223-7783-01Size:0.02 mg
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Background
PROM1 is a pentaspan transmembrane glycoprotein that localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation (1) . Mutations in this gene have been shown to result in retinitis pigmentosa (2) . Expression of this gene is also associated with several types of cancer (3) .
NCBI Gene ID
8842
Swiss Prot
O43490
Accession Number
NP_006008
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Stem Cell, Cancer
Purification
PROM1 antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1205 - Jurkat Cell Lysate
Concentration
1 mg/mL
Buffer
PROM1 Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
PROM1 antibody can be stored at 4˚ C up to one year. Antibodies should not be exposed to prolonged high temperatures.
Fragment
IgG
Specificity
PROM1 antibody is human, mouse and rat reactive. Multiple isoforms of PROM1 are known to exist.
Symbol
PROM1
Positive Control 2
Cat. No. 17-005 - Jurkat Cell Slide
NCBI Official Name
Prominin 1
NCBI Organism
Homo sapiens
Background Reference 01
Yin AH, Miraglia S, Zanjani ED, et al. AC133, a novel marker for human hematopoietic stem and progenitor cells. Blood 1997; 90:5002-12.
Background Reference 02
Zhang Q, Zulfiqar F, Xiao X, et al. Severe retinitis pigmentosa mapped to 4p15 and associated with a novel mutation in the PROM1 gene. Hum. Genet. 2007; 122:293-9.
Background Reference 03
Tabu K, Bizen N, Taga T, et al. Gene regulation of Prominin-1 (CD133) in normal and cancerous tissues. Adv. Exp. Med. Biol. 2013; 777:73-85.
Other Product Names
PROM1 Antibody: RP41, AC133, CD133, MCDR2, STGD4, CORD12, PROML1, MSTP061, Prominin-1, Antigen AC133
Tested Applications
ELISA, WB, ICC, IF
Protein ID
5174387
Physical Properties
Liquid

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