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CXCL12 Antibody

CAT: 0223-7591-01Size: 0.02 mgDry Ice: NoHazardous: No
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CAT#:0223-7591-01Size:0.02 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The CXCL12 protein, also known as SDF1, is a stromal cell-derived alpha chemokine member of the intercrine family. CXCL12 functions as the ligand for the G-protein coupled receptor, chemokine (C-X-C motif) receptor 4 (CXCR4) and CXCR7, and plays a role in many diverse cellular functions, including embryogenesis, immune surveillance, inflammation response, tissue homeostasis, and tumor growth and metastasis (reviewed in 1) . Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections (2) .
NCBI Gene ID
6387
Swiss Prot
P48061
Accession Number
NP_001171605
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology
Purification
CXCL12 antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1201 - HeLa Cell Lysate
Concentration
1 mg/mL
Buffer
CXCL12 antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
CXCL12 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.
Fragment
IgG
Specificity
CXCL12 antibody is human and mouse reactive. Multiple isoforms of CXCL12 are known to exist.
Symbol
CXCL12
Positive Control 2
Cat. No. 17-001 - HeLa Cell Slide
NCBI Official Name
Chemokine (C-X-C motif) ligand 12
NCBI Organism
Homo sapiens
Background Reference 01
Timotijevic G, Mostarica Stojkovic M, and Miljkovic D. CXCL12: role in neuroinflammation. Int. J. Biochem. Cell Biol. 2012; 44:838-41.
Background Reference 02
Reiche EM, Ehara Watanabe MA, Bonametti AM, et al. The effect of stromal cell-derived factor 1 (SDF1/CXCL12) genetic polymorphism on HIV-1 disease progression. Int. J. Mol. Med. 2006; 18:785-93.
Other Product Names
CXCL12 Antibody: IRH, PBSF, SDF1, TLSF, TPAR1, SCYB12, SDF1A, SDF1B, Stromal cell-derived factor 1, C-X-C motif chemokine 12, SDF-1
Tested Applications
ELISA, WB, ICC
Protein ID
296011023
Physical Properties
Liquid

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