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PHF14 Antibody

CAT: 0223-7485-01Size: 0.02 mgDry Ice: NoHazardous: No
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CAT#:0223-7485-01Size:0.02 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
PHF14, a novel plant homology domain (PHD) transcription factor, controls the proliferation of mesenchymal cells by regulating PDGFR alpha expression in embryonic development (1) . PHD finger transcription factors are concerned with transcriptional regulation by interacting with modified histones (2), and dysregulation of several genes encoding PHD finger transcription factors, such as ING1 and RBP2, has been found in human cancer diseases suggesting these factors have an important role for cancer cell proliferation. PHF14 is a potential target for new treatments of lung fibrosis (1, 3) .
NCBI Gene ID
9678
Swiss Prot
O94880
Accession Number
NP_055475
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Stem Cell
Purification
PHF14 Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1210 - HEK293 Cell Lysate
Concentration
1 mg/mL
Buffer
PHF14 Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
PHF14 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year.
Fragment
IgG
Specificity
PHF14 antibody is human, mouse and rat reactive. Multiple isoforms of PHF14 are known to exist.
Symbol
PHF14
Positive Control 2
Cat. No. 17-010 - HEK293 Cell Slide
NCBI Official Name
PHD finger protein 14
NCBI Organism
Homo sapiens
Background Reference 01
Kitagawa M, Takebe A, Ono Y, et al. Phf14, a novel regulator of mesenchyme growth via platelet-derived growth factor (PDGF) receptor-a. J. Biol. Chem. 2012; 287:27983-96.
Background Reference 02
Musco G and Peterson P. PHD finger of autoimmune regulator: an epigenetic link between the histone modifications and tissue-specific antigen expression in thymus. Epigenetics 2008; 3:310-4.
Background Reference 03
Musselman CA and Kutateladze TG. PHD fingers: epigenetic effectors and potential drug targets. Mol. Interv. 2009; 9:314-23.
Other Product Names
PHF14 Antibody : KIAA0783, PHD finger protein 14
Tested Applications
ELISA, WB, IF
Protein ID
55769548
Physical Properties
Liquid

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