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TNFAIP2 Antibody

CAT: 0223-7051-01Size: 0.02 mgDry Ice: NoHazardous: No
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CAT#:0223-7051-01Size:0.02 mg
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Background
TNFAIP2 Antibody: TNFAIP2, also known as B94, is a TNF-a-regulated gene that is expressed in endothelial cells, peripheral blood cells, and mature sperm. Recently, elevated TNFAIP2 expression was observed in nasopharyngeal carcinoma, and high expression of TNFAIP2 was significantly correlated with higher levels of cell migration, invasion and metastasis, suggesting that TNFAIP2 may serve as a useful prognostic indicator for nasopharyngeal carcinoma. TNFAIP2 has also been implicated as part of the viral-sensing circuit of the innate immune response.
NCBI Gene ID
7127
Swiss Prot
Q03169
Accession Number
NP_006282
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle
Purification
TNFAIP2 Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1204 - K562 Cell Lysate
Concentration
1 mg/mL
Buffer
TNFAIP2 Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
TNFAIP2 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
72 kDa
Fragment
IgG
Specificity
At least two isoforms of TNFAIP2 are known to exist; this antibody will detect both isoforms. This antibody is predicted to not cross-react with TNFAIP3.
Symbol
TNFAIP2
Positive Control 2
Cat. No. 17-004 - K-562 Cell Slide
NCBI Official Name
Tumor necrosis factor, alpha-induced protein 2
NCBI Organism
Homo sapiens
Background Reference 01
Wolf FW, Sarma V, Deldin M, et al. B94, a primary response gene inducible by tumor necrosis factor-alpha, is expressed in developing hematopoietic cells and the sperm acrosome. J. Biol. Chem. 1994; 269:3633-40.
Background Reference 02
Chen LC, Chen CC, Liang Y, et al. A novel role for TNFAIP2: its correlation with invasion and metastasis in nasopharyngeal carcinoma. Mod. Pathol. 2011; 24:175-84.
Background Reference 03
Chevrier N, Mertins P, Artyomov MN, et al. Systematic discovery of TLR signaling components delineates viral-sensing circuits. Cell 147:853-67.
Other Product Names
TNFAIP2 Antibody: B94, EXOC3L3, Tumor necrosis factor alpha-induced protein 2, Primary response gene B94 protein, TNF alpha-induced protein 2
Tested Applications
ELISA, WB, IF
Protein ID
26051240
Physical Properties
Liquid

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