SLC35D3 Antibody

CAT: 0223-6547-01Size: 0.02 mgDry Ice: NoHazardous: No
CAT#:0223-6547-01Size:0.02 mg
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Background
SLC35D3 Antibody: The solute carrier family SLC35 consists of at least 17 proteins that act as nucleotide sugar transporters localized to the Golgi apparatus and endoplasmic reticulum. The novel protein SLC35D3 is highly homologous to SLC35D1 and SLC35D2, both of which transport UDP-glucuronic acid and UDP-N-acetylgalactosamine, suggesting that SLC35D3 is also involved in the transport of nucleotide sugars. It has been suggested that SLC35D3 regulates platelet dense granules, lysosome-related organelles which contain high concentrations of several biologically important low molecular weight molecules necessary for normal blood homeostasis.
NCBI Gene ID
340146
Swiss Prot
Q5M8T2
Accession Number
AAH87842
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
SLC35D3 Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1201 - HeLa Cell Lysate
Concentration
1 mg/mL
Buffer
SLC35D3 Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
SLC35D3 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Fragment
IgG
Specificity
At least two isoforms of SLC35D3 are known to exist; this antibody will recognize both isoforms. SLC35D3 antibody is predicted to not cross-react with SLC35D1 or SLC35D2.
Symbol
SLC35D3
Positive Control 2
Cat. No. 17-001 - HeLa Cell Slide
NCBI Official Name
Solute carrier family 35, member D3
NCBI Organism
Homo sapiens
Background Reference 01
Ishida N and Kawakita M. Molecular physiology and pathology of the nucleotide sugar transporter family (SLC35) . Pflugers Arch. 2004; 447:768-75.
Background Reference 02
Suda T, Kamiyama S, Suzuki M, et al. Molecular cloning and characterization of a human multisubstrate specific nucleotide-sugar transporter homologous to Drosophila fringe connection. J. Biol. Chem. 2004; 279:26469-74.
Background Reference 03
Chintala S, Tan J, Gautam R, et al. The Slc35d3 gene, encoding an orphan nucleotide sugar transporter, regulates platelet-dense granules. Blood 2007; 109:1533-40
Other Product Names
SLC35D3 Antibody: FRCL1, bA55K22.3, FRCL1, Solute carrier family 35 member D3, Fringe connection-like protein 1
Tested Applications
ELISA, WB, ICC, IF
Protein ID
56912198
Physical Properties
Liquid

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