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TYW3 Antibody

CAT: 0223-6377-01Size: 0.02 mgDry Ice: NoHazardous: No
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CAT#:0223-6377-01Size:0.02 mg
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Background
TYW3 Antibody: TYW3 is an enzyme that participates in the wybutosine-tRNA (Phe) biosynthesis pathway. Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome. TYW3 is involved in a multistep enzymatic reaction that stabilizes codon-anticodon base-pairing during the ribosomal decoding process, thereby ensuring correct translation.
NCBI Gene ID
127253
Swiss Prot
Q6IPR3
Accession Number
Q6IPR3
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Homeostasis
Purification
TYW3 Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1203 - A549 Cell Lysate
Concentration
1 mg/mL
Homology
Predicted species reactivity based on immunogen sequence: Bovine: (94%), Pig: (94%)
Buffer
TYW3 Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
TYW3 antibody can be stored at 4 ˚ C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Fragment
IgG
Specificity
TYW3 antibody is predicted to not cross-react with other TYW protein family members. At least two isoforms of TYW3 are known to exist; this antibody will detect both isoforms.
Symbol
TYW3
NCBI Official Name
TRNA-yW synthesizing protein 3 homolog (S. cerevisiae)
NCBI Organism
Homo sapiens
Background Reference 01
Noma A and Suzuki T. Ribonucleome analysis identified enzyme genes responsible for wybutosine synthesis. Nucleic Acids Symp. Ser. (Oxf) 2006; 65-6.
Background Reference 02
Noma A, Kirino Y, Ikeuchi Y, et al. Biosynthesis of wybutosine, a hyper-modified nucleoside in eukaryotic phenylalanine tRNA. EMBO J. 2006; 25:2142-54
Other Product Names
TYW3 Antibody: C1orf171, C1orf171, tRNA wybutosine-synthesizing protein 3 homolog, tRNA-yW-synthesizing protein 3
Tested Applications
ELISA, WB
Protein ID
42734381
Physical Properties
Liquid

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