ApoA5 Antibody

• Background:

  ApoA5 Antibody: Apoliproprotein A-V is a protein coded by the APOA5 gene, which is highly expressed in the liver. This protein is responsible for binding to lipids in the liver and forming lipoproteins. In recent years, the gene has been used as a marker for measuring cardiovascular health as well as metabolic syndromes. The protein plays an important role in plasma triglyceride (lipid) regulation within the body. Although only expressed in the liver, APOA5 has functions both inside and outside of cells, as well as modulating triglyceride homeostasis in areas like the gut. Mutations in the APOA5 gene have up to 3 times the risk for the development of cardiovascular disease in association studies. Dietary studies support this lack of metabolic regulation by showing that any mutation in APOA5 will result in higher triglyceride levels than control groups when dieting.

• NCBI Gene ID:

  419802

• Swiss Prot:

  E1BT17

• Accession Number:

  XP_417939

• Host:

  Rabbit

• Reactivity:

  Human, Chicken

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle

• Purification:

  ApoA5 Antibody is affinity chromatography purified via peptide column.

• Positive Control:

  Cat. No. 1304 - Human Liver Tissue Lysate

• Concentration:

  1 mg/mL

• Buffer:

  ApoA5 Antibody is supplied in PBS containing 0.02% sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  ApoA5 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Fragment:

  IgG

• Symbol:

  APOA5

• NCBI Official Name:

  Apolipoprotein A-V

• NCBI Organism:

  Gallus gallus

• Background Reference 01:

  De Luis Roman et al. Nutrients 2022, 14 (12) : 2427.

• Background Reference 02:

  Jacob et al. BMC nephrology 2022, 23, 307.

• Background Reference 03:

  May-Zhang et al. Biochimica et biophysica acta (BBA) - Molecular and cell biology of lipids 2022, 1867 (9) : 159185.

• Other Product Names:

  ApoA5 Antibody:

• Tested Applications:

  ELISA, WB

• Protein ID:

  118101989

• Physical Properties:

  Liquid