ApoA4 Antibody

• Background:

  ApoA4 Antibody: Apolipoprotein A4 (also known as ApoA-IV) is a plasma protein that is O-linked glycoprotein after proteolytic processing. ApoA4 is a major constituent of HDL and it also can be found on the surface of newly synthesized chylomicrons. The physiological function of ApoA4 is not completely identified so far, but several evidences from vitro studies indicate that this apolipoprotein involves in several steps of the reverse cholesterol transport pathway, which transports cholesterol from peripheral cells back to the liver.

• NCBI Gene ID:

  337

• Swiss Prot:

  P06727

• Accession Number:

  NP_990269

• Host:

  Rabbit

• Reactivity:

  Human, Chicken

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle

• Purification:

  ApoA4 Antibody is affinity chromatography purified via peptide column.

• Positive Control:

  Chicken Small Intestine Lysate

• Concentration:

  1 mg/mL

• Buffer:

  ApoA4 Antibody is supplied in PBS containing 0.02% sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  ApoA4 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Fragment:

  IgG

• Symbol:

  APOA4

• NCBI Official Name:

  Apolipoprotein A-IV

• NCBI Organism:

  Gallus gallus

• Background Reference 01:

  Karathanasis SK, Oettgen P, Haddad IA, et al. Structure, evolution, and polymorphisms of the human apolipoprotein A4 gene (APOA4) . Proc. Natl. Acad. Sci. 1986; 83:8457-61

• Background Reference 02:

  Kamboh MI, Friedlaender JS, Ahn YI et al. A common deletion polymorphism in the apolipoprotein A4 gene and tis significance in lipid metabolism. Arterioscler. Thromb. 1994; 14:656-62.

• Background Reference 03:

  Kronenberg F, Stuhlinger M, Trenkwalder E, et al. Low apolipoprotein A-IV plasma concentrations in men with coronary artery disease. J. Am. Coll. Cardiol., 2000; 36:751-7

• Background Reference 04:

  Von Eckardstein A, Huang Y, Wu S, et al. Lipoproteins containing apolipoprotein A-IV but not apolipoprotein A-I take up and esterify cell-derived cholesterol in plasma. Arterioscler Thromb Vasc Biol. 1995; 15:1755-63.

• Other Product Names:

  ApoA4 Antibody: Apolipoprotein A-IV, Apolipoprotein A4, Apo-AIV

• Tested Applications:

  ELISA, WB

• Protein ID:

  71773110

• Physical Properties:

  Liquid