ApoA1 Antibody

• Background :

  ApoA1 Antibody: Apolipoprotein A1 (ApoA1) is the major protein component of high density lipoprotein (HDL) in plasma, which is correlated with cardiovascular disease. ApoA1 is synthesized in the liver and small intestine and promotes cholesterol efflux from tissues to the liver for excretion. It is a cofactor for lecithin cholesterolacyltransferase (LCAT), the enzyme responsible for the formation of most plasma cholesteryl esters. Defects in ApoA1 are associated with HDL deficiency, Tangier disease, and systemic non-neuropathic amyloidosis.

• NCBI Gene ID :

  335

• Swiss Prot :

  P02647

• Accession Number :

  P02647

• Host :

  Rabbit

• Reactivity :

  Human, Chicken

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cancer, Cell Cycle

• Purification :

  ApoA1 Antibody is affinity chromatography purified via peptide column.

• Positive Control :

  Chicken Liver Lysate

• Concentration :

  1 mg/mL

• Buffer :

  ApoA1 Antibody is supplied in PBS containing 0.02% sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  ApoA1 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Fragment :

  IgG

• Symbol :

  APOA1

• NCBI Official Name :

  Apolipoprotein A-I

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Zhu X, Wu G, Zeng W, et al. Cysteine mutants of human apolipoprotein A-I: a study of secondary structural and functional properties. J. Lipid Res. 2005; 46:1303-11

• Background Reference 02 :

  Sorci-Thomas MG, Prack MM, Dashti N, et al. Differential effects of dietary fat on the tissue-specific expression of the apolipoprotein A-I gene: relationship to plasma concentration of high density lipoproteins. J. Lipid Res. 1989; 30:1397-403

• Background Reference 03 :

  Lai C-Q, Parnell LD, and Ordovas JM. The APOA1 /C3/A4/A5 gene cluster, lipid metabolism and cardiovascular disease risk. Curr. Opin. Lipid. 2005; 16:153-66

• Other Product Names :

  ApoA1 Antibody: Apolipoprotein A-I, Apolipoprotein A1, Apo-AI

• Tested Applications :

  ELISA, WB

• Protein ID :

  113992

• Physical Properties :

  Liquid