Products for Research Use Only
RegisterLogin

RBM35B Antibody

CAT: 0223-6187-01Size: 0.02 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-6187-01Size:0.02 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
RBM35B Antibody: RBM35A, also known as ESRP2, is a mRNA splicing factor that with its related protein RBM35A (ESRP1) are coordinators of an epithelial cell-type-specific splicing program. Both RBM35B and RBM35A are involved in posttranscriptional regulation of a number of genes such as FGFR2, CD44, CTNND1, and ENAH by exerting a differential effect on protein translation via 5' UTRs of mRNAs, suggesting that these proteins are global regulators of an epithelial regulatory network. Loss of this global ESRP-regulated epithelial splicing programme induces the phenotypic changes in cell morphology that are observed during the epithelial-mesenchymal transition.
NCBI Gene ID
80004
Swiss Prot
Q9H6T0
Accession Number
NP_079215
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Stem Cell
Purification
RBM35B Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1302 - Human Lung Tissue Lysate
Concentration
1 mg/mL
Homology
Predicted species reactivity based on immunogen sequence: Rat: (80%)
Buffer
RBM35B Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
RBM35B antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Fragment
IgG
Specificity
RBM35B antibody is predicted to not cross-react with other RBM35/ESRP family members. At least two isoforms of RBM35B are known to exist; this antibody will detect both isoforms.
Symbol
ESRP2
Positive Control 2
Cat. No. 10-101 - Human Lung Tissue Slide
NCBI Official Name
Epithelial splicing regulatory protein 2
NCBI Organism
Homo sapiens
Background Reference 01
Warzecha CC, Sato TK, Nabet B, et al. ESRP1 and ESRP2 are epithelial cell-type-specific regulators of FGFR2 splicing. Mol Cell. 2009; 33:591-601.
Background Reference 02
Warzecha CC, Jiang P, Amirikian K, et al. An ESRP-regulated splicing programme is abrogated during the epithelial-mesenchymal transition. EMBO J. 2010; 29:3286-300.
Background Reference 03
Warzecha CC, Shen S, Xing Y, et al. The epithelial splicing factors ESRP1 and ESRP2 positively and negatively regulate diverse types of alternative splicing events. RNA Biol. 2009; 6:546-62.
Other Product Names
RBM35B Antibody: RBM35B, RBM35B, PP7059, Epithelial splicing regulatory protein 2, RNA-binding motif protein 35B
Tested Applications
ELISA, WB, IHC-P, IF
Protein ID
45935393
Physical Properties
Liquid

Related Products

CatalogName
6187PRBM35B Peptide
23-951RBM15B Antibody
29-762RBM35A Antibody
6185-002mgRBM35A Antibody
6185-01RBM35A Antibody
6185-01mgRBM35A Antibody
14-867RBM12B Antibody
19-501RBM15 Antibody
25-648RBM34 Antibody
29-512RBM45 Antibody

Alternative Products

CatalogName
GWB-218CF6RBM35B Antibody
A08004Anti-RBM35B ESRP2 Antibody
GTR17867328RBM35B Rabbit Polyclonal Antibody
SL19772R-01Rabbit Anti-RBM35B/ESRP2 antibody
ARP37559_T100-25ULRBM35B Antibody - N-terminal region
GTR18387947RBM35B Rabbit Polyclonal Antibody (HRP)
GTR18387945RBM35B Rabbit Polyclonal Antibody (Biotin)
OAPB01253-100UG-BiotinRBM35B Antibody : Biotin (OAPB01253-Biotin)
GTR18387948RBM35B Rabbit Polyclonal Antibody (FITC)
527642-01RBM35B

Popular Products