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ZNF687 Antibody

CAT: 0223-6067-01Size: 0.02 mgDry Ice: NoHazardous: No
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CAT#:0223-6067-01Size:0.02 mg
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Background
ZNF687 Antibody: The zinc finger protein 687 (ZNF687) was initially identified as a translocation partner gene with RUNX1 in patients with acute myeloid leukemia (AML) . Little is known of the function of the ZNF687 protein, but it has been shown to weakly interact with the Ring1/Rnf2 RING finger protein member of the Polycomb group of proteins, suggesting it may be involved in the chromatin-modifying complexes essential for embryonic development and stem cell renewal. Other evidence suggests that ZNF687 may be part of a transcriptional network that also includes ZNF592 and ZMYMD8.
NCBI Gene ID
57592
Swiss Prot
Q8N1G0
Accession Number
NP_065883
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Stem Cell
Purification
ZNF687 Antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL
Homology
Predicted species reactivity based on immunogen sequence: Mouse: (94%)
Buffer
ZNF687 Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
ZNF687 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Fragment
IgG
Specificity
ZNF687 antibody is human specific. At least three isoforms of ZNF687 are known to exist; this antibody will detect the the two largest isoforms.
Symbol
ZNF687
NCBI Official Name
Zinc finger protein 687
NCBI Organism
Homo sapiens
Background Reference 01
Nguyen TT, Ma LN, Slovak ML, et al. Identification of novel Runx1 (AML1) translocation partner genes SH3D19, YTDf2, and ZNF687 in acute myeloid leukemia. Genes Chromo. Cancer 2006; 45:918-32.
Background Reference 02
Sanchez C, Sanchez I, Demmers JA, et al. Proteomics analysis of Ring1/Rnf2 interactors identifies a novel complex with the Fbxl10/Jhdm1B histone demethylase and the Bcl6 interacting corepressor. Mol. Cell Proteomics 2007; 6:820-34.
Background Reference 04
Malovannaya A, Lanz RB, Jung SY, et al. Analysis of the human endogenous coregulator complexome. Cell 2011; 145:787-99.
Other Product Names
ZNF687 Antibody: KIAA1441, Zinc finger protein 687
Tested Applications
ELISA, IHC-P
Protein ID
24308227
Physical Properties
Liquid

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