MFSD2A Antibody

CAT: 0223-6025-01Size: 0.02 mgDry Ice: NoHazardous: No
CAT#:0223-6025-01Size:0.02 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
MFSD2A Antibody: Multidrug transporters, such as MFSD2A, are membrane proteins that expel a wide spectrum of cytotoxic compounds from the cell and render cells resistant to multiple drugs. Major Facilitator Superfamily (MFS) members are capable of transporting various substrates such as sugars, polyols, drugs, neurotransmitters, amino acids, peptides, and inorganic anions, although most members are substrate-specific. MFSD2A is a novel lung cancer tumor suppressor gene that regulates cell cycle progression and matrix attachment and has recently been described as the human receptor for syncytin-2, a retrovirus-derived protein mediating fusion of placental trophoblasts. MFSD2A is expressed in many tissues and is highly induced in liver and brown adipose tissue (BAT) during fasting. The activation of the betaAR signaling pathway plays a major role in the induction of MFSD2A expression during adaptive thermogenesis.
NCBI Gene ID
492810
Swiss Prot
Q5U3U7
Accession Number
NP_001129965
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle
Purification
MFSD2A Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1462 - Rat Lung Tissue Lysate
Concentration
1 mg/mL
Buffer
MFSD2A Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
MFSD2A antibody can be stored at 4˚ C up to one year. Antibodies should not be exposed to prolonged high temperatures.
Fragment
IgG
Symbol
Mfsd2aa
NCBI Official Name
Major facilitator superfamily domain containing 2aa
NCBI Organism
Danio rerio
Background Reference 01
Fluman N and Bibi E. Bacterial multidrug transport through the lens of the major facilitator superfamily. Biochim. Biophys. Acta.2009; 1794:738-47.
Background Reference 02
Law CJ, Maloney PC, and Wang DN. Ins and outs of major facilitator superfamily antiporters. Annu. Rev. Microbiol.2008; 62:289-305.
Background Reference 03
Spinola M, Falvella FS, Colombo F, et al. MFSD2A is a novel lung tumor suppressor gene modulating cell cycle and matrix attachment. Mol. Cancer2010;9:62.
Background Reference 04
Angers M, Uldry M, Kong D, et al. Mfsd2a encodes a novel major facilitator superfamily domain-containing protein highly induced in brown adipose tissue during fasting and adaptive thermogenesis. Biochem. J.2008; 416:347-55.
Other Product Names
MFSD2A Antibody: mfsd2a, zgc:101615, mfsd2a, Major facilitator superfamily domain-containing protein 2A-A
Tested Applications
ELISA, WB, IHC-P, IF
Protein ID
55925395
Physical Properties
Liquid

Related Products

CatalogName
6025PMFSD2A Peptide
6027-01MFSD2B Antibody
6027-002mgMFSD2B Antibody
6027-01mgMFSD2B Antibody
43-002MFSD6 Antibody
60-586MFSD4 Antibody
6023-002mgMFSD1 Antibody
6023-01mgMFSD1 Antibody
6023-01MFSD1 Antibody
30-753MFSD3 Antibody

Alternative Products

CatalogName
E037724MFSD2A Antibody
MBS2524487-01MFSD2A Polyclonal Antibody
STJ11100244Anti-Mfsd2a antibody
MBS9448162-01MFSD2A Conjugated Antibody
323807-01MFSD2A

Popular Products