PLEKHM2 Antibody

• Background :

  PLEKHM2 Antibody: PLEKHM2, also known as SKIP, is a member of the M family of Pleckstrin homology domain-containing proteins. While little is known of PLEKHM2, a recent study examining differential gene expression in human hematopoietic stem cells has shown it to be specifically expressed in stem cells, suggesting that PLEKHM2 may play a role in erythroid commitment and development. Other studies have shown that PLEKHM2 is required for interaction with the Salmonella virulence factor SifA for Salmonella pathogenesis, suggesting that PLEKHM2 has cellular roles other than in the developing embryo.

• NCBI Gene ID :

  23207

• Swiss Prot :

  Q8IWE5

• Accession Number :

  CAH72018

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Stem Cell

• Purification :

  PLEKHM2 Antibody is affinity chromatography purified via peptide column.

• Positive Control :

  Cat. No. 1463 - Rat Brain Tissue Lysate

• Concentration :

  1 mg/mL

• Buffer :

  PLEKHM2 Antibody is supplied in PBS containing 0.02% sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  PLEKHM2 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Fragment :

  IgG

• Symbol :

  PLEKHM2

• Positive Control 2 :

  Cat. No. 10-201 - Human Liver Tissue Slide

• NCBI Official Name :

  Pleckstrin homology domain containing, family M (with RUN domain) member 2

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Liu X-L, Yuan J-Y, Zhang J-W, et al. Differential gene expression in human hematopoietic stem cells specified toward erythroid, megakaryotic, and granulocytic lineage. J. Leuk. Biol.2007; 82:986-1002.

• Background Reference 02 :

  Diacovich L, Dumont A, Lafitte D, et al. Interaction between the SifA virulence factor and its host target SKIP is essential for Salmonella pathogenesis. J. Biol. Chem.2009; 284:33151-60.

• Other Product Names :

  PLEKHM2 Antibody: SKIP, KIAA0842, SKIP, Pleckstrin homology domain-containing family M member 2, Salmonella-induced filaments A and kinesin-interacting protein, PH domain-containing family M member 2

• Tested Applications :

  ELISA, WB, IHC-P, IF

• Protein ID :

  55666400

• Physical Properties :

  Liquid