Gp120 Antibody

CAT: 0223-4777-01Size: 0.02 mgDry Ice: NoHazardous: No
CAT#:0223-4777-01Size:0.02 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Gp120 Antibody: Human immunodeficiency virus type 1 (HIV-1) entry into target cells is directed by the envelope (Env) glycoproteins, which are present on the surface of HIV-1 virion or infected cells in the form of trimers consisting of gp120/gp41 complexes. The surface subunit, gp120, initiates the entry process by interacting sequentially with the CD4 receptor and a co-receptor CCR5 or CXCR4, thereby inducing a conformational change that allows the transmembrane (TM) gp41 subunit to mediate fusion between viral and target cell membranes. Cleavage of Env into its gp120 and gp41 components is necessary for activation of its fusogenic activity.
NCBI Gene ID
155971
Swiss Prot
Q6BBS3
Accession Number
AAB05604
Host
Goat
Reactivity
Virus
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Infectious Disease
Purification
Gp120 Antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL
Buffer
Gp120 Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Gp120 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Fragment
IgG
Applications Notes
Gp120 antibody can be used for detection of gp120 by Western blot at 1 μ g/mL.
Symbol
Env
NCBI Official Name
Envelope glycoprotein
NCBI Organism
Human immunodeficiency virus 1
Background Reference 01
Pinter A. Roles of HIV-1 Env variable regions in viral neutralization and vaccine development. Curr. HIV Res.2007; 5:542-53.
Background Reference 02
Alkhatib G and Berger EA. HIV coreceptors: from discovery and designation to new paradigms and promise. Eur. J. Med. Res.2007; 12:375-84.
Other Product Names
Gp120 Antibody: Envelope glycoprotein gp160
Tested Applications
ELISA, WB
Protein ID
1465781
Physical Properties
Liquid

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