Rift Valley Fever Virus Antibody

• Background:

  Rift Valley Fever Virus Antibody: Rift Valley Fever (RFV) virus is an arthropod-borne virus endemic to Africa that infects humans and animals that is transmitted predominantly by mosquitoes. During human infections, symptoms can range from benign fever to severe encephalitis and fatal hepatitis with hemorrhagic fever. The Bunyaviridae family of viruses to which the RVF virus belongs are spherical enveloped viruses with a tripartite RNA genome of negative or ambisense polarity. The three segments are referred to as the L, M, and S segments. The L and M segments are negative polarity and code fore the L-dependent RNA polymerase and glycoprotein precursor respectively. The S segment is of ambisense polarity and encodes the nucleoprotein and non-structural proteins. This RVF virus antibody was derived from a peptide sequence near the center of the polyprotein precursor translated from the M segment. It will therefore detect both the precursor and the Glycoprotein G1.

• NCBI Gene ID:

  9538296

• Swiss Prot:

  P03518

• Accession Number:

  P03518

• Host:

  Rabbit

• Reactivity:

  Virus

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Infectious Disease

• Purification:

  Rift Valley Fever Virus Antibody is affinity chromatography purified via peptide column.

• Concentration:

  1 mg/mL

• Buffer:

  Rift Valley Fever Virus Antibody is supplied in PBS containing 0.02% sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Rift Valley Fever Virus antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Fragment:

  IgG

• Applications Notes:

  RVF virus antibody can detect 10ng RVF virus peptide in ELISA at 1 μ g/mL.

• Symbol:

  RVFV_sM_gp1

• NCBI Official Name:

  Envelope glycoprotein

• NCBI Organism:

  Rift Valley fever virus

• Background Reference 01:

  Morrill JC and McClain DJ. Epidemiology and pathogenesis of the Rift Valley fever and other phleboviruses, p. 281-93 in H Fraenkel-Conrat and RR Wagner (ed.) The viruses. Plenum Press, New York, NY.

• Background Reference 02:

  Schmaljohn C and Hooper JW. Bunyaviridae: the viruses and their replication, 4th ed. Lippincott Williams & Wilkins, Philadelphia, PA.

• Background Reference 03:

  Giorgi C, Accardi L, Nicoletti M, et al. Sequences and coding strategies of the S RNAs of Toscana and Rift Valley fever viruses compared to those of Punta Toro, Sicilian sandfly fever, and Uukuniemi viruses. Virology1991; 180:738-53.

• Other Product Names:

  Rift Valley Fever Virus Antibody: Envelope glycoprotein, M polyprotein, GP

• Tested Applications:

  ELISA

• Protein ID:

  1174956

• Physical Properties:

  Liquid