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FABP7 Antibody

CAT: 0223-4259-01Size: 0.02 mgDry Ice: NoHazardous: No
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CAT#:0223-4259-01Size:0.02 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
FABP7 Antibody: FABP7 was initially isolated from a human fetal brain cDNA library and whose mRNA was expressed in adult brain and muscle tissues at low levels. The protein encoded by this gene is a member of the fatty acid binding protein (FABPs) family, a group of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs are thought to play roles in fatty acid uptake, transport, and metabolism. FABP7 is a downstream gene of the Pax6 transcription factor and has been suggested to be essential for the maintenance of neuroepithelial cells during early cortical development. More recently, FABP7 was found to be frequently expressed in melanomas. Down-regulation of FABP7 through RNAi expression could reduce in vitro cell proliferation and Matrigel invasion, suggesting that FABP7 may be a potential target for the development of diagnostic and therapeutic tools.
NCBI Gene ID
2173
Swiss Prot
O15540
Accession Number
EAW48166
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Homeostasis
Purification
FABP7 Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1311 - Human Breast Tissue Lysate
Concentration
1 mg/mL
Homology
Predicted species reactivity based on immunogen sequence: Bovine: (100%), Chicken: (94%), Rat: (94%), Mouse: (88%)
Buffer
FABP7 Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
FABP7 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Fragment
IgG
Symbol
FABP7
Positive Control 2
Cat. No. 10-001 - Human Breast Tissue Slide
NCBI Official Name
Fatty acid binding protein 7, brain
NCBI Organism
Homo sapiens
Background Reference 01
Shimizu F, Watanabe TK, Shinomiya H, et al. Isolation and expression of a cDNA for human brain fatty acid-binding protein (B-FABP) . Biochim. Biophys. Acta1997; 1354:24-8.
Background Reference 02
Chmurzynska A. The multigene family of fatty acid-binding proteins (FABPs) : function, structure and polymorphism. J. Appl. Genet.2006; 47:39-48.
Background Reference 03
Arai Y, Funatsu N, Numayama-Tsuruta K, et al. Role of FABP7, a downstream gene of pax6, in the maintenance of neuroepithelial cells during early embryonic development of the rat cortex. J. Neurosci.2005; 25:9752-61.
Background Reference 04
Goto Y, Matsuzaki Y, Kurihara S, et al. A new melanoma antigen fatty acid-binding protein 7, involved in proliferation and invasion, is a potential target for immunotherapy and molecular target therapy. Cancer Res.2006; 66:4443-9.
Other Product Names
FABP7 Antibody: MRG, BLBP, FABPB, B-FABP, MRG, Fatty acid-binding protein, brain, Brain lipid-binding protein
Tested Applications
ELISA, WB, IHC-P
Protein ID
119568551
Physical Properties
Liquid

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