CTRP5 Antibody

CAT: 0223-3573-01Size: 0.02 mgDry Ice: NoHazardous: No
CAT#:0223-3573-01Size:0.02 mg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CTRP5 Antibody: Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines. One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-alpha-related proteins (CTRPs) 1-7. Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues. These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene. CTRP5 has been suggested to be involved in age-related macular degeneration.
NCBI Gene ID
114902
Swiss Prot
Q9BXJ0
Accession Number
AAQ88749
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
CTRP5 Antibody is immunoaffinity purified IgG.
Positive Control
Cat. No. 1223 - Caco-2 Cell Lysate
Concentration
1 mg/mL
Homology
Predicted species reactivity based on immunogen sequence: Rat: (93%), Mouse: (93%)
Buffer
CTRP5 Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
CTRP5 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Fragment
IgG
Specificity
Adipokine proteins are often highly modified post-translationally and migrate in SDS-PAGE at positions other than their predicted size.
Symbol
C1QTNF5
NCBI Official Name
C1q and tumor necrosis factor related protein 5
NCBI Organism
Homo sapiens
Background Reference 01
CTRP5 antibody can be stored at 4˚ C, stable for one year. Fantuzzi G. Adipose tissue, adipokines, and inflammation. J. Allergy Clin. Immunol. 2005; 115:911-9.
Background Reference 02
Tsao T-S, Lodish HF, and Fruebis J. ACRP30, a new hormone controlling fat and glucose metabolism. Euro. J. Pharmacol. 2002; 440:213-21.
Background Reference 03
Wong GW, Wang J, Hug C, et al. A family of Acrp30/ adiponectin structural and functional paralogs. Proc. Natl. Acad. Sci. USA 2004; 101:10302-7.
Background Reference 04
Shapiro L and Scherer PE. The crystal structure of a complement-1q family protein suggests an evolutionary link to tumor necrosis factor. Curr. Biol. 1998; 8:335-8.
Other Product Names
CTRP5 Antibody: CTRP5, CTRP5, UNQ303/PRO344, Complement C1q tumor necrosis factor-related protein 5
Tested Applications
ELISA, WB
Protein ID
37181891
Physical Properties
Liquid

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