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CTRP3 Antibody

CAT: 0223-3565-01Size: 0.02 mgDry Ice: NoHazardous: No
CAT#:0223-3565-01Size:0.02 mg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CTRP3 Antibody: Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines. One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-alpha-related proteins (CTRPs) 1-7. Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene. It has been suggested that CTRP3 may play a role in skeletal development.
NCBI Gene ID
114899
Swiss Prot
Q9BXJ4
Accession Number
NP_852100
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
3565
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Validation
Recombinant Protein Test (Figure 2) : Anti-CTRP3 antibodies (3565) detected human CTRP3 recombinant protein. Recombinant Protein Test3565
Field of Research
Signal Transduction
Purification
CTRP3 Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1401 - Mouse Heart Tissue Lysate
Concentration
1 mg/mL
Buffer
CTRP3 Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
CTRP3 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Fragment
IgG
Specificity
Multiple isoforms of CTRP3 are known to exist. CTRP3 antibody is predicted to not recognize other members of the CTRP protein family.
Isoform
Human CTRP3 has 3 isoforms, including isoform 1 (246aa, 27kD), isoform 2 (198aa, 22kD) and isoform 3 (319aa, 35kD) . Mouse CTRP3 has one isoform (246aa, 27kD) and Rat CTRP3 also has one isoform (319aa, 35kD) . 3565 can detect human, mouse and rat.
Symbol
C1QTNF3
Positive Control 2
Cat. No. 1203 - A549 Cell Lysate
Positive Control 3
Cat. No. 1205 - Jurkat Cell Lysate
Positive Control 4
Cat. No. 1282 - 3T3/NIH Cell Lysate
NCBI Official Name
C1q and tumor necrosis factor related protein 3
NCBI Organism
Homo sapiens
Background Reference 01
Fantuzzi. J. Allergy Clin. Immunol. 2005; 115:911-9.
Background Reference 02
Tsao et al. Euro. J. Pharmacol. 2002; 440:213-21.
Background Reference 03
Wong et al. Proc. Natl. Acad. Sci. USA 2004; 101:10302-7.
Background Reference 04
Shapiro and Scherer. Curr. Biol. 1998; 8:335-8.
Other Product Names
CTRP3 Antibody: CORS, CORCS, CTRP3, CORS26, C1ATNF3, CORS-26, UNQ753/PRO1484, Complement C1q tumor necrosis factor-related protein 3, Collagenous repeat-containing sequence 26 kDa protein
Tested Applications
ELISA, WB, IHC-P, IF
Protein ID
62739183
Physical Properties
Liquid

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