Products for Research Use Only
RegisterLogin

WNV Core Antibody

CAT: 0223-3433-01Size: 0.02 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-3433-01Size:0.02 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
WNV Core Antibody: West Nile Virus (WNV) is a member of the Flaviviridae, a plus-stranded virus family that includes St. Louis encephalitis virus, yellow fever virus, and Dengue virus. WNV was initially isolated in 1937 in the West Nile region of Uganda and has become prevalent in Africa, Asia, and Europe. It has rapidly spread across the United States with cases being observed in every continental state. Virus particles consist of a dense core made up of the core/capsid protein encapsulating the RNA genome surrounded by a membrane envelope embedded with envelope and matrix proteins which play a major role for WNV entry into target cells. The viral core protein is thought to contribute to the WNV-associated inflammation via apoptosis induced though the caspase-9 pathway as delivery of core gene delivery into the striatum of mouse brain and skeletal muscle resulted in cell death and inflammation.
NCBI Gene ID
912267
Swiss Prot
P06935
Accession Number
NP_776011
Host
Rabbit
Reactivity
Virus
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Infectious Disease
Purification
WNV Core Antibody is affinity chromatography purified via peptide column.
Concentration
1 mg/mL
Buffer
WNV Core Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
WNV Core antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Fragment
IgG
Applications Notes
WNV Core antibody can be used for the detection of the WNV Core protein in ELISA. It will detect 10 ng of free peptide at 1 μ g/mL.
Symbol
WNVgp1
NCBI Official Name
Anchored core protein C
NCBI Organism
West Nile virus
Background Reference 01
Gould LH and Fikrig E. West Nile virus: a growing concern. J. Clin. Invest. 2004; 113:1102-7.
Background Reference 02
Chu JJ, Rajamanonmani R, Li J, et al. Inhibition of West Nile virus entry by using a recombinant domain III from the envelope glycoprotein. J. Gen. Virol. 2005; 86:405-12.
Background Reference 03
Chu JJ and Ng ML. Interaction of West Nile virus with α v β 3 integrin mediates virus entry into cells. J. Biol. Chem. 2004; 279:54533-41.
Background Reference 04
Yang JS, Ramanathan MP, Muthumani K, et al. Induction of inflammation by West Nile Virus capsid through the caspase-9 apoptotic pathway. Emerg. Infect. Dis. 2002; 8:1379-84.
Other Product Names
WNV Core Antibody : Genome polyprotein, Core protein, NS1
Tested Applications
ELISA
Protein ID
27735299
Physical Properties
Liquid

Related Products

CatalogName
3433PWNV Core Peptide
PSI-1809West Nile virus (WNV) Protein Detection Set
3435-01mgWest Nile Virus Core Antibody
3435-01West Nile Virus Core Antibody
3435-002mgWest Nile Virus Core Antibody
91-772Brevican Core Protein Recombinant Protein
3435PWest Nile Virus Core Peptide
53-327Hepatitis C virus core Recombinant Protein
53-315Hepatitis B virus core Recombinant Protein
53-324Hepatitis C virus core Recombinant Protein

Alternative Products

CatalogName
MBS7146114Core Antibody
GWB-88D890HCV Core Antibody
6136-50USP34 Core Antibody
MBS534350-01Histone Core antibody
253510WNV Core Antibody
abx137186-01HBV Core Antibody
250683HCV-Core Antibody
PT_73818-01Hepatitis C Virus Core, Mouse antibody (HCV Core Antibody)
abx137069-01Human Chorionic Gonadotropin Beta Core (HCG-b core) Antibody
10-S05FSalmonella antibody (LPS core)

Popular Products