Products for Research Use Only
RegisterLogin

CX3CL1 Antibody

CAT: 0223-2099-01Size: 0.02 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-2099-01Size:0.02 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
CX3CL1 Antibody: Chemokines are a family of proteins associated with the trafficking of leukocytes in immune surveillance and inflammatory cell recruitment. They are classified based on the positions of key cysteine residues. CX3CL1 is a CX3C chemokine known to induce adhesion and migration of leukocytes mediated by a membrane-bound and soluble form respectively. Recent experiments have shown that CX3CL1 can suppress the production of nitrous oxide, interleukin-6, and TNF-α in activated microglia and neuronal cells, suggesting that it may act as an intrinsic inhibitor against neurotoxicity by activated microglia. Its receptor, CX3CR1, also functions as a co-receptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by CX3CL1.
NCBI Gene ID
6376
Swiss Prot
P78423
Accession Number
AAB50014
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Infectious Disease, Innate Immunity, Chemokines & Cytokines
Purification
CX3CL1 Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1285 - C2C12 Cell Lysate
Concentration
1 mg/ml
Homology
Predicted species reactivity based on immunogen sequence: Rat: (79%)
Buffer
CX3CL1 Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
CX3CL1 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Fragment
IgG
Symbol
CX3CL1
NCBI Official Name
Chemokine (C-X3-C motif) ligand 1
NCBI Organism
Homo sapiens
Background Reference 01
Bajetto A, Bonavia R, Barbero S, et al. Chemokines and their receptors in the central nervous system. Front. Neuroendocrinol. 2001; 22:147-84.
Background Reference 02
Umehara H, Goda S, Imai T, et al. Fractalkine, a CX3C-chemokine, functions predominantly as an adhesion molecule in monocytic cell line THP-1. Immunol. Cell. Biol. 2001; 79:298-302.
Background Reference 03
Mizuno T, Kawanokuchi J, Numata K, et al. Production and neuroprotective functions of fractalkine in the central nervous system. Brain Res. 2003; 979:65-70.
Background Reference 04
Combadiere C, Salzwedel K, Smith ED, et al. Identification of CX3CR1. A chemotactic receptor for the human CX3C chemokine fractalkine and a fusion coreceptor for HIV-1. J. Biol. Chem.1998; 273:23799-804.
Other Product Names
CX3CL1 Antibody: NTN, NTT, CXC3, CXC3C, SCYD1, ABCD-3, C3Xkine, fractalkine, neurotactin, FKN, A-152E5.2, Fractalkine, C-X3-C motif chemokine 1
Tested Applications
ELISA, WB, IP
Protein ID
1899259
Physical Properties
Liquid

Related Products

CatalogName
43-578CX3CL1 / fractalkine Antibody
2099PCX3CL1 Peptide
90-453CX3CL1 Recombinant Protein
43-578PCX3CL1 / fractalkine Peptide
92-343CX3CL1 Recombinant Protein
91-417CX3CL1 Recombinant Protein
90-452CX3CL1 Recombinant Protein
96-859CX3CL1 Recombinant Protein
10-961Quetmolimab (CX3CL1) - Research Grade Biosimilar
2201-01mgCX3CR1 Antibody

Alternative Products

CatalogName
70R-16678CX3CL1 antibody

Popular Products