Anti D

• Description :

  The test procedures recommended for the use of this reagent are based upon the agglutination (clumping) of red cells carrying the D antigen in the presence of an Anti-D antibody. This test serum reacts negatively with erythrocytes of category DVI.

• Storage Temperature :

  2 - 8 °C

• Notes :

  The observations of Levine and Stetson in 1939 and of Landsteiner and Weiner in 1940 provided the basis for current understanding of the clinical significance and laboratory detection of RhD antigen. Approximately 15% of Caucasians lack the RhD antigen and are easily stimulated by RhD+ve pregnancy or blood transfusion to produce Anti-D. This may cause haemolytic disease of the newborn or severe haemolytic transfusion reactions.