Atp2a1 (NM_007504) Mouse Recombinant Protein

• Background:

  Key regulator of striated muscle performance by acting as the major Ca (2+) ATPase responsible for the reuptake of cytosolic Ca (2+) into the sarcoplasmic reticulum (PubMed:21697544, PubMed:22961106, PubMed:25640239, PubMed:26816378) . Catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction (PubMed:21697544, PubMed:22961106, PubMed:25640239, PubMed:26816378) .[UniProtKB/Swiss-Prot Function]

• Synonyms:

  SERCA1

• Gene ID:

  11937

• UniProt:

  Q8R429

• Accession Number mRNA:

  NM_007504

• Chromosomal Location:

  7 69.04 cM

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  109.4 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Atp2a1

• Species:

  Mouse

• Protein ID:

  NP_031530

• Overview:

  Purified recombinant protein of Mouse ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 (Atp2a1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/11937

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q8R429

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_007504

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_031530