Adamts8 (NM_013906) Mouse Recombinant Protein

• Background:

  This gene encodes a member of "a disintegrin and metalloproteinase with thrombospondin motifs" (ADAMTS) family of multi-domain matrix-associated metalloendopeptidases that have diverse roles in tissue morphogenesis and pathophysiological remodeling, in inflammation and in vascular biology. This gene is expressed in mouse lung, heart and macrophage-rich areas of atherosclerotic plaques. The encoded preproprotein undergoes proteolytic processing to generate an active, zinc-dependent aggrecanase enzyme. This gene is located adjacent to a related ADAMTS gene on chromosome 9. [provided by RefSeq, May 2016]

• Synonyms:

  METH-2; METH2

• Gene ID:

  30806

• UniProt:

  F8VQ15

• Accession Number mRNA:

  NM_013906

• Chromosomal Location:

  9 16.49 cM

• Expression System:

  HEK293T

• Tag:

  C-MYC/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

• Molecular Weight:

  99.4 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  Adamts8

• Species:

  Mouse

• Protein ID:

  NP_038934

• Overview:

  Purified recombinant protein of Mouse a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 8 (Adamts8), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/30806

• Uniprot URL:

  https://www.uniprot.org/uniprot/F8VQ15

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_013906

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_038934