PPME1 (NM_016147) Human Recombinant Protein

• Background:

  This gene encodes a protein phosphatase methylesterase localized to the nucleus. The encoded protein acts on the protein phosphatase-2A catalytic subunit and supports the ERK pathway through dephosphorylation of regulatory proteins. It plays a role in malignant glioma progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012]

• Synonyms:

  ABDH19; PME-1

• Gene ID:

  51400

• UniProt:

  Q9Y570, A0A140VK39

• Accession Number mRNA:

  NM_016147

• Chromosomal Location:

  11q13.4

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome

• Molecular Weight:

  42.1 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  PPME1

• Species:

  Human

• Protein ID:

  NP_057231

• Overview:

  Recombinant protein of human protein phosphatase methylesterase 1 (PPME1)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/51400

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9Y570

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_016147

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_057231