14 3 3 eta (YWHAH) (NM_003405) Human Recombinant Protein

• Background:

  This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and bovine orthologs. This gene contains a 7 bp repeat sequence in its 5' UTR, and changes in the number of this repeat have been associated with early-onset schizophrenia and psychotic bipolar disorder. [provided by RefSeq, Jun 2009]

• Synonyms:

  YWHA1

• Gene ID:

  7533

• UniProt:

  Q04917, A0A024R1K7, Q9H4N8

• Accession Number mRNA:

  NM_003405

• Chromosomal Location:

  22q12.3

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Cell cycle, Neurotrophin signaling pathway, Oocyte meiosis

• Field of Research:

  Cell cycle, Neurotrophin signaling pathway, Oocyte meiosis

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome, Transcription Factors

• Molecular Weight:

  28 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  YWHAH

• Species:

  Human

• Protein ID:

  NP_003396

• Overview:

  Recombinant protein of human tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide (YWHAH)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/7533

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q04917

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_003405

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_003396