EB2 (MAPRE2) (NM_014268) Human Recombinant Protein

• Background:

  The protein encoded by this gene shares significant homology to the adenomatous polyposis coli (APC) protein-binding EB1 gene family. This protein is a microtubule-associated protein that is necessary for spindle symmetry during mitosis. It is thought to play a role in the tumorigenesis of colorectal cancers and the proliferative control of normal cells. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2012]

• Synonyms:

  CSCSC2; EB1; EB2; RP1

• Gene ID:

  10982

• UniProt:

  Q15555, A0A024RC33

• Accession Number mRNA:

  NM_014268

• Chromosomal Location:

  18q12.1-q12.2

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Function:

  Druggable Genome

• Molecular Weight:

  36.9 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  MAPRE2

• Species:

  Human

• Protein ID:

  NP_055083

• Overview:

  Recombinant protein of human microtubule-associated protein, RP/EB family, member 2 (MAPRE2), transcript variant 1

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/10982

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q15555

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_014268

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_055083