PRPF4 (NM_004697) Human Recombinant Protein

• Background:

  The protein encoded by this gene is part of a heteromeric complex that binds U4, U5, and U6 small nuclear RNAs and is involved in pre-mRNA splicing. The encoded protein also is a mitotic checkpoint protein and a regulator of chemoresistance in human ovarian cancer. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2016]

• Synonyms:

  HPRP4; HPRP4P; PRP4; Prp4p; RP70; SNRNP60

• Gene ID:

  9128

• UniProt:

  O43172

• Accession Number mRNA:

  NM_004697

• Chromosomal Location:

  9q32

• Expression System:

  HEK293T

• Tag:

  C-Myc/DDK

• Related Pathways:

  Spliceosome

• Field of Research:

  Spliceosome

• Concentration:

  >50 ug/mL as determined by microplate BCA method

• Purity:

  > 80% as determined by SDS-PAGE and Coomassie blue staining

• Form:

  Liquid

• Buffer:

  25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

• Molecular Weight:

  58.3 kDa

• Storage Conditions:

  Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  PRPF4

• Species:

  Human

• Protein ID:

  NP_004688

• Overview:

  Recombinant protein of human PRP4 pre-mRNA processing factor 4 homolog (yeast) (PRPF4)

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/9128

• Uniprot URL:

  https://www.uniprot.org/uniprot/O43172

• Accession Number mRNA URL:

  https://www.ncbi.nlm.nih.gov/nuccore/NM_004697

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/nuccore/NP_004688